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Baltazar Gomez-Mancilla Selected Research

3- (6- methylpyridin- 2- ylethynyl)cyclohex- 2- enone- O- methyloxime

10/2013Chronic treatment with MPEP, an mGlu5 receptor antagonist, normalizes basal ganglia glutamate neurotransmission in L-DOPA-treated parkinsonian monkeys.
3/2013MPEP, an mGlu5 receptor antagonist, reduces the development of L-DOPA-induced motor complications in de novo parkinsonian monkeys: biochemical correlates.
7/2011Metabotropic glutamate receptor type 5 in levodopa-induced motor complications.

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Baltazar Gomez-Mancilla Research Topics

Disease

12Parkinson Disease (Parkinson's Disease)
01/2021 - 05/2010
11Dyskinesias (Dyskinesia)
10/2017 - 06/2010
10Fragile X Syndrome (Martin Bell Syndrome)
01/2021 - 01/2011
6Intellectual Disability (Idiocy)
01/2018 - 01/2011
3Alzheimer Disease (Alzheimer's Disease)
07/2011 - 02/2008
2Dementia (Dementias)
01/2021 - 02/2008
2Autism Spectrum Disorder
01/2018 - 04/2012
2Cognitive Dysfunction
11/2016 - 03/2012
2Huntington Disease (Huntington's Disease)
09/2015 - 03/2015
1Dysthymic Disorder
01/2021
1Orthostatic Hypotension (Postural Hypotension)
01/2021
1Syncope (Fainting)
01/2021
1Depressive Disorder (Melancholia)
01/2021
1Neurodevelopmental Disorders
01/2018
1Spinal Cord Injuries (Spinal Cord Injury)
01/2018
1Tardive Dyskinesia
10/2017
1Obsessive-Compulsive Disorder (Disorder, Obsessive-Compulsive)
01/2017
1Schizophrenia (Dementia Praecox)
11/2016
1Nausea
01/2016
1Fatigue
01/2016
1Chorea (Rheumatic Chorea)
03/2015
1Dizziness (Lightheadedness)
09/2014
1Pain (Aches)
02/2014
1Headache (Headaches)
02/2014
1Migraine Disorders (Migraine)
02/2014
1Sleep Deprivation
01/2013
1Major Depressive Disorder (Major Depressive Disorders)
01/2013
1Atrophy
01/2010
1Nervous System Diseases (Neurological Disorders)
09/2008
1Amyloidosis
02/2008
1Disease Progression
02/2008
1Amyloid Plaque
02/2008
1Neurodegenerative Diseases (Neurodegenerative Disease)
04/2006
1Pathologic Processes
04/2006

Drug/Important Bio-Agent (IBA)

11Levodopa (L Dopa)FDA LinkGeneric
01/2016 - 05/2010
7mavoglurantIBA
01/2017 - 01/2011
6Proteins (Proteins, Gene)FDA Link
11/2018 - 04/2006
61- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA
11/2014 - 06/2010
5Metabotropic Glutamate Receptors (Metabotropic Glutamate Receptor)IBA
09/2014 - 05/2010
5Glutamic Acid (Glutamate)FDA Link
09/2014 - 09/2008
4Metabotropic Glutamate 5 ReceptorIBA
01/2018 - 03/2012
3Biomarkers (Surrogate Marker)IBA
01/2021 - 04/2006
3Pharmaceutical PreparationsIBA
01/2021 - 03/2014
3Fragile X Mental Retardation ProteinIBA
01/2018 - 03/2012
3Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA
11/2016 - 11/2014
33- (6- p- tolylpyridin- 3- yloxy)- 1- azabicyclo(2.2.2)octaneIBA
11/2016 - 11/2014
33- (6- methylpyridin- 2- ylethynyl)cyclohex- 2- enone- O- methyloximeIBA
10/2013 - 07/2011
2AMPA Receptors (AMPA Receptor)IBA
02/2014 - 10/2013
2N-Methylaspartate (NMDA)IBA
10/2013 - 01/2013
2Therapeutic UsesIBA
05/2011 - 06/2010
1hydroxide ionIBA
01/2021
1Rivastigmine (Exelon)FDA LinkGeneric
01/2021
1AntibodiesIBA
01/2018
1Dopamine Receptors (Dopamine Receptor)IBA
10/2017
1Metoclopramide (Reglan)FDA LinkGeneric
10/2017
1Antipsychotic Agents (Antipsychotics)IBA
10/2017
1Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA
01/2017
1EnkephalinsIBA
09/2015
1Substance PIBA
09/2015
16- fluoro- 2- (4- (pyridin- 2- yl)but- 3- yn- 1- yl)imidazo(1,2- a)pyridineIBA
09/2014
1Sumatriptan (Imigran)FDA LinkGeneric
02/2014
1selurampanelIBA
02/2014
1propionic acid (potassium propionate)IBA
02/2014
1CGP 39653IBA
10/2013
1LY 341495IBA
10/2013
1Ro 25-6981IBA
10/2013
1Ro 48-8587IBA
10/2013
16-methyl-2-(phenylethynyl)pyridineIBA
03/2013
1Glutamate Receptors (Glutamate Receptor)IBA
01/2013
1Ionotropic Glutamate ReceptorsIBA
01/2013
1Amantadine (Aman)FDA LinkGeneric
01/2013
1Excitatory Amino Acid AntagonistsIBA
04/2012
1Leucine (L-Leucine)FDA Link
11/2011
1Phosphotransferases (Kinase)IBA
11/2011
1LigandsIBA
07/2011
1Presenilin-1IBA
07/2011
1acivicin (AT 125)IBA
05/2011
15' Untranslated Regions (5' UTR)IBA
01/2011
1Dihydrotachysterol (AT 10)IBA
06/2010
1amyloid beta-protein (1-42)IBA
01/2010
1Serine (L-Serine)FDA Link
02/2008
1Peptides (Polypeptides)IBA
04/2006

Therapy/Procedure

7Therapeutics
01/2017 - 06/2011
1Precision Medicine
01/2021
1Activities of Daily Living (ADL)
06/2011